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apalutamide will minimize the level or result of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with prescription drugs that are CYP2C19 substrates may lead to reduced exposure to those remedies.Convey to your Health care service provider at